Table of Content


Summer 2019, Vol. 27 No. 2

Hong Kong J. Dermatol. Venereol. (2019) 27, 59-67

Original Article

Linking the PASI of sufferers from moderate and severe psoriasis to an increase of carotid intima-media thickness: a cross-sectional study


A Martinez-Lopez, L Salvador-Rodriguez, A Rodriguez-Tejero, G Blasco-Morente, J Tercedor-Sanchez, S Arias-Santiago


Psoriasis is a multsystemic disease which has been related with comorbidities such as metabolic syndrome and arteriosclerosis through a psoriasis-related inflammatory chronic state. In order to assess the relationship of psoriasis with carotid intima-media thickness (IMT), 100 moderate-to-severe psoriatic patients were studied. Increased PASI score was associated with a higher IMT. Additionally, a higher IMT was observed with the increasing of erythrocyte sedimentation rate. In conclusion, patients with moderate-to-severe psoriasis are at higher risk of an increased IMT.


Keywords: Atherosclerosis; chronic inflammation; intima-media thickness; psoriasis; TNF-alpha

關鍵詞: 動脈粥樣硬化、慢性炎症、內膜中層厚度、銀屑病、甲型腫瘤壞死因子