Table of Content


Autumn 2018, Vol. 26 No. 3

Hong Kong J. Dermatol. Venereol. (2018) 26, 113-121

Review Article

Approach to pigmented skin disorders in children


YC Giam 唐玉琴


Pigmented problems in children covers a wide area, and a simple approach may be to divide them into hypopigmentation and hyperpigmentation. Understanding the biology of the melanocyte pigment and the mechanisms allow one to diagnose the hypopigmented ones, The hyperpigmented problems are more complex and causal factors are many, some follows pigment patterns, e.g. lentigines, café au lait macules, some functions like the xerodermas and many are gene mutations like incontinentia pigmenti. Also included are acquired factors and environmental factors. Most of these childhood lesions are of cosmetic concern and may not need treatment. However, other organ systems may be involved in syndromes. Therefore other associated features in the clinical presentation play an important role in the diagnosis.


Keywords: Biology of melanocytes, Genetics, Hyperpigmentation, Hypopigmentation, Pigmentary disorders

關鍵詞: 黑素細胞生物學、遺傳學、色素沉著過度、色素減退、色素異常