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Summer 2018, Vol. 26 No. 2

Hong Kong J. Dermatol. Venereol. (2018) 26, 94


Answers to Dermato-venereological Quiz

Answers to Dermato-venereological Quiz

SM Wong 黃思敏, RCW Su 蘇志慰, ETY Cheung 張天恩

  1. The clinical diagnosis is Lichen planus. Differential diagnoses include cutaneous lupus erythematosus (discoid lupus erythematosus), lichen simplex chronicus, and actinic dermatitis/cheilitis.
  2. The typical histopathological findings include: irregular epidermal acanthosis, accentuation of the granular layer, liquefactive degeneration of the basal layer, and a band-like dermal infiltrate of lymphocytes.
  3. The physician should examine the oral cavity and genitalia (mons pubis, labia majora, labia minora) to look for lacy-white reticulation/Wickham striae and erosions.
  4. The treatment options include: topical potent corticosteroids, topical calcineurin-inhibitors, intra-lesional corticosteroids to hypertrophic lesions. For more severe or recalcitrant disease, immunosuppressants such low-dose weekly methotrexate can be considered.