Table of Content


Winter 2017, Vol. 25 No. 4

Hong Kong J. Dermatol. Venereol. (2017) 25, 187-191

Case Report

A case of primary cutaneous Langerhans cell sarcoma clinically mimicking pyogenic granuloma


O Kwon 權五勝, KD Park 朴璟德, H Chung 鄭炫, JB Park 朴栽福, JY Park 朴志英, DH Shin 申東薰, J Park 朴埈秀


Langerhans cell sarcoma (LCS) is a rare neoplasm of Langerhans cell lineage with prominent malignant cytological features. Currently, complex histological evaluation is required for accurate diagnosis and treatments providing have not been standardised due to its rarity. A thirty-five-year-old female patient presented with a solitary coin-sized dome-shaped mass on the left shin for two months. Histology confirmed Langerhans cell sarcoma with immunohistochemical stains being positive for S-100, Ki-67 and CD1a. Herein, we present a rare case of a single-site LCS in light of expanding the currently available knowledge on LCS and to underline the importance of immunohistochemical analysis since Langerhans cell sarcoma may cause diagnostic confusion due to clinical and histological similarities with other diseases.


Keywords: Langerhans cell sarcoma, malignant melanoma, pyogenic granuloma

關鍵詞: 朗格漢斯細胞肉瘤、惡性黑色素瘤、化膿性肉芽腫