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Winter 2017, Vol. 25 No. 4

Hong Kong J. Dermatol. Venereol. (2017) 25, 161-169


Original Article

Clinical indicators of rosacea progression: a topographic evaluation according to subtype and severity

玫瑰痤瘡進展的臨床指標:根據亞型和嚴重度進行面部分佈評估

JS Hong 洪宗秀, G Jo 曺光鉉, HS Park 朴炫宣, HS Yoon 尹鉉善, S Cho 趙昭衍

Abstract

In this study, 704 patients were analyzed and classified into four subtypes (erythematotelangiectatic (ETR), papulopustular (PPR), combined (ETR + PPR), phymatous (PHY)). The most common subtype was ETR (55.7%), followed by combined type (22.6%). The cheek was the most commonly affected site (89.9%), followed by the nose (56.5% ), glabella (37.8%), nasolabial fold (17.2%) and periorbital area (9.8%). The glabella was significantly more frequently affected in the combined type (69.2%) than in ETR (28.3%), regardless of severity. The response rate was significantly different between ETR and combined type (10.9% vs 26.0%). In Korean patients with rosacea, pure PPR is much less common than the combined subtype. Glabellar and nasal involvement can be an early marker of subtype transition from ETR to the combined subtype.

本研究對704例患者進行分析,將其分為紅斑血管擴張型、丘疹膿皰型、混合型和鼻瘤型四個亞型。當中最常見的亞型是紅斑血管擴張型(55.7%),其次是混合型(22.6%)。最常受影響的部位是面頰(89.9%),其次是鼻(56.5%)、眉間(37.8%)、鼻唇褶(17.2%)和眼週邊位置(9.8%)。無論嚴重程度如何,混合型(69.2%)的眉間影響率遠高於紅斑血管擴張型(28.3%)。而紅斑血管擴張型與混合型的治療成效有顯著性差異(10.9%對26.0%)。在韓國的玫瑰痤瘡患者中,純紅斑血管擴張型比混合型(即從紅斑血管擴張型進展的丘疹膿皰型)亞型來得罕見。眉間和鼻的影響則可能是從紅斑血管擴張型演變為混合型的早期徵兆。

Keywords: Prognosis of rosacea, rosacea progression, severity of rosacea, subtypes of rosacea, topographical difference

關鍵詞: 玫瑰痤瘡的預後、玫瑰痤瘡進展、玫瑰痤瘡的嚴重程度、玫瑰痤瘡的亞型、面部分佈差異