Archive

Autumn 2017, Vol. 25 No. 3

Hong Kong J. Dermatol. Venereol. (2017) 25, 128-132

Case Report

A case of Sweet's syndrome with marked facial swelling and fluid collection

一例有明顯面部腫脹並積液的史維特症候群

JE Seol 薛禎恩, SH Park 朴蘇熙, DH Kim 金道亨, JN Kang 姜情暖, H Kim 金孝鎮

Abstract

A 43-year-old woman presented with a one-day history of painful erythematous patches with swelling on face, accompanied by fever of 38.4°C. Laboratory tests showed leukocytosis with neutrophil predominance and increased erythrocyte sedimentation rate and C-reactive protein level. Histopathological examination revealed dense neutrophil infiltration in dermis. She was diagnosed with Sweet syndrome and treated with systemic corticosteroids, after which she showed clinical improvement. As the corticosteroids were being tapered, however, facial swelling developed with focal fluid collection. Incision and drainage were performed, and cyclosporine, colchicine, and dapsone were administered. After 16 weeks, she showed marked clinical improvement.

一名四十三歲的女性，因持續一天的臉部腫脹和伴隨的疼痛紅斑及攝氏38.4度發熱而求診。化驗所檢查顯示白血球增多，當中以嗜中性粒細胞為主；另外，紅細胞沉降率和C反應蛋白水平升高。組織病理學檢查發現病灶真皮層有嗜中性粒細胞浸潤。她被診斷為患有史維特症候群，施以全身性皮質類固醇治療後，皮膚情況得到臨床改善。但隨著皮質類固醇逐漸減量，面部卻又再次腫脹並有局部積液。在積液處進行了切口及引流手術，並改用環孢菌素、秋水仙鹼和氨苯碸等藥物治療。16週後，患者的臨床症狀有顯著改善。

Keywords: Sweet syndrome

關鍵詞: 史維特症候群