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Autumn 2016, Vol. 24 No. 3

Hong Kong J. Dermatol. Venereol. (2016) 24, 155-156


Dermato-venereological Quiz

Dermato-venereological Quiz

CMT Cheung 張敏彤, MM Chang 張苗, PCL Choi 蔡祥龍

A middle-aged Chinese woman presented with 6-month history of an itchy skin rash. She had underlying hypertension, diabetes mellitus, obesity, chronic kidney disease and history of colonic cancer with resection done 10 years previously. The eruption occurred on the shins, the trunk and the back. There was no history of insect bites or use of new medications. Examination revealed multiple erythematous round papules and papulonodules with a keratotic centre (Figure 1). She was otherwise afebrile and clinically well. A punch skin biopsy was obtained on the leg for histological evaluation (Figures 2a & 2b).

Figure 1

Figure 2 Skin biopsy. Haematoxylin & eosin stain, magnification x100 (a) and x200 (b).

Questions

1. What are the differential diagnoses?
2. What does the biopsy show?
3. What is the diagnosis?
4. What is the treatment?