Table of Content


Autumn 2016, Vol. 24 No. 3

Hong Kong J. Dermatol. Venereol. (2016) 24, 141-144

Case Report

A case of generalised pustular psoriasis mimicking acute generalised exanthematous pustulosis


CS Park 朴贊仙 and SY Jung 鄭素榮


Differentiating between acute generalised exanthematous pustulosis (AGEP) and generalised pustular psoriasis (GPP) is very challenging because of clinical and histopathological similarities. A 60-year-old woman presented with pustular eruption and fever. She had taken dapsone and zaltoprofen for five days. Laboratory findings revealed neutrophil dominant leucocytosis and histopathological findings revealed a subcorneal spongiform pustule. Under the diagnosis of AGEP, she was treated with systemic steroids. However, the pustular lesions were aggravated after steroid reduction. In light of GPP, she was treated with acitretin and showed a good response. This case highlights the difficulty of differentiation between GPP and AGEP.


Keywords: Acute generalised exanthematous pustulosis, dapsone, generalised pustular psoriasis, pustular eruption, subcorneal pustule

關鍵詞: 急性泛發性發疹性膿皰症、達普頌(氨苯碸)、泛發性膿皰型銀屑病、膿皰性皮疹、角質層下膿皰