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Autumn 2016, Vol. 24 No. 3

Hong Kong J. Dermatol. Venereol. (2016) 24, 135-139


Case Report

Mastocytosis: the other great mimicker in dermatology

肥大細胞增多症:皮膚科中的另一模仿能手

R Ramalingam, AM Affandi, N Azizan, TG Ng, BR Lee

Abstract

Mastocytosis represents a disease spectrum characterised by mast cell hyperplasia in one or more organs, with the skin being the most commonly affected organ. Due to its highly variable cutaneous manifestations, it is not uncommon for mastocytosis to closely resemble certain dermatological diseases and therefore, may be easily misdiagnosed. Here we report two extraordinary cases of mastocytosis with variable cutaneous lesions mimicking two common dermatological diseases. We also hope that by highlighting these cases, mastocytosis would be considered as an important differential diagnosis when encountering dermatological diseases with diagnostic dilemmas.

肥大細胞增多症代表著一個疾病譜系,其特徵是一個或多個器官中的肥大細胞增生,皮膚為最常受影響的器官。由於它千變萬化的皮膚表現,肥大細胞增多症常表面上看似其他皮膚病,容易地被誤診。我們在此報告兩宗肥大細胞增多症的特殊病例,各有疑似其他兩種常見皮膚病的皮膚損變化。通過這兩宗病例的啟示,我們亦寄望當醫生遇到一些困難的皮膚疾病診斷時,會把肥大細胞增多症納入其中一個重要的鑑別診斷考慮。

Keywords: Cutaneous lymphoma, leprosy, Malaysia, mastocytosis

關鍵詞: 皮膚淋巴瘤、痳瘋病、馬來西亞、肥大細胞增多症