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Autumn 2015, Vol. 23 No. 3

Hong Kong J. Dermatol. Venereol. (2015) 23, 113-117


Review Article

Treatment of vitiligo: medical treatment, phototherapy and surgical treatment

白蝕的治療:藥物治療、光療及手術治療

ECY Chu 朱灼欣

Abstract

Vitiligo is a depigmentary disorder which causes significant psychological distress. Treatment of vitiligo aims to minimise disease progression and achieve cosmetically pleasing repigmentation. Topical corticosteroids are commonly used as the first-line therapy. Studies showed that topical calcineurin inhibitors and topical vitamin D3 analogues are also effective treatment options of vitiligo. Phototherapy should be reserved for patients who fail topical therapy. For the group of patients not responding to conservative treatment modalities, surgical treatment is the only option. Understanding all the available treatment options helps us to choose the appropriate treatment for our patients.

白蝕是一種可引致顯著心理困擾的皮膚色素脫失症。其治療目的是盡力防止患處擴大,同時使脫色部位達致美容上令人滿意的膚色復原。外用皮質類固醇是常用的第一線治療。研究發現外用鈣調神經磷酸酶抑製劑和外用維生素D3類似物亦是有效的外用治療選擇。光療則應留待給對外用藥物治療無效者。如果連光療亦不見效,手術治療便是終極的選擇。只要了解所有可用的療法,我們便能為白蝕病人選擇最適切的治療方案。

Keywords: Depigmentation, medical treatment, phototherapy, surgical treatment, vitiligo

關鍵詞: 色素脫失、藥物治療、光療、手術治療、白蝕