Table of Content


Winter 2014, Vol. 22 No. 4

Hong Kong J. Dermatol. Venereol. (2014) 22, 191-193

Paediatric Dermatology Column: Case Report

Silvery hair syndromes: report of familial cases of Griscelli syndrome in three siblings


A Molina-Leyva and MA Fernandez-Pugnaire


Silvery hair is a rare clinical feature, common in a group of rare syndromes, which usually present in the paediatric age group termed together as "silvery hair syndromes". We report a consanguineous family in which three out of four siblings had silvery hair and neurological deficits and were diagnosed to have Griscelli syndrome. The diagnosis of Griscelli syndrome in our cases was based on clinical findings with severe neurological impairment in the absence of immunodeficiency and the characteristic findings of hair light microscopy.


Keywords: Griscelli syndrome, silvery hair syndromes

關鍵詞: 格里塞利綜合徵、銀髮綜合徵