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Autumn 2014, Vol. 22 No. 3

Hong Kong J. Dermatol. Venereol. (2014) 22, 135-139


Case Report

Desmoplastic trichoepithelioma; a new case and review of the literature with emphasis on its differential diagnosis

結締組織增生性毛髮上皮瘤;新病例一則和文獻綜述,並偏重探討其鑑別診斷

M Concha-Rogazy, S Alvarez-Veliz, P Del Barrio-Díaz, JE Carrasco-Zuber, S Gonzalez-Bombardiere

Abstract

Trichoepithelioma is a benign neoplasm with hair follicle differentiation that may present as solitary, multiple or desmoplastic forms. This report describes a case of desmoplastic trichoepithelioma, an uncommon adnexal tumour with an incidence of 2 per 10,000. Desmoplastic trichoepithelioma is a benign lesion, clinically and histologically similar to other cutaneous tumours, and presents a true diagnostic challenge. The clinical criteria, histopathological features and immunohistochemical profile are discussed with emphasis on its differential diagnosis.

毛髮上皮瘤為良性瘤細胞增生,可呈單一、多個或在結締組織中,在向毛髮結構分化過程中形成。此報告描述了一宗結締組織增生性毛髮上皮瘤──一種罕見的皮脂腺上皮瘤,發病率約為每萬人中兩例。毛髮上皮瘤是一種良性病變,從臨床學及組織學的角度來講與其他皮膚腫瘤類似,因而構成了診斷上的困難。本報告探討其臨床診斷標準、組織病理特點以及免疫組化概 要,並注重研究其鑒別診斷。

Keywords: Cutaneous tumours, adnexal neoplasms, basal cell carcinoma, skin cancer

關鍵詞: 皮膚腫瘤、皮脂腺上皮瘤、基底細胞癌、皮膚癌