Table of Content


Summer 2014, Vol. 22 No. 2

Hong Kong J. Dermatol. Venereol. (2014) 22, 85-89

Case Report

Cutaneous phaeohyphomycosis in an immunocompromised host


YXE Tay 鄭予昕, JY Pan 潘君毅, SSJ Lee 李尚思


Phaeohyphomycosis is an infection caused by dematiaceous fungi in which fungi are present as yeast-like cells or hyphal elements. We report a case of phaeohyphomycosis of the right forearm in a 72 year-old patient with low grade B cell lymphoma and background endogenous eczema. An unusual feature of this case is that tissue fungal cultures isolated two fungal species, namely Exophiala jeanselmei and Cladophialophora species. We seek to highlight phaeohyphomycosis as an emerging mycosis in immunocompromised patients. Physicians should also maintain a high clinical suspicion for unusual skin signs in immunocompromised individuals as they are more prone to developing opportunistic skin infections.

暗色絲孢黴病是暗色黴菌造成的皮膚病之一。在這種暗色絲孢黴病裡,暗色黴菌可存在為酵母細胞和菌絲。我們報告一位七十二歲患有低度惡性B細胞淋巴瘤和內源性濕疹病人的右前臂中,發現有暗色絲孢黴病的情況。此病例不尋常之處為皮膚抽樣培養出不僅一類,而是兩類暗色黴菌 − 甄氏外瓶黴及Cladophialophora 種。在免疫系統功能受影響的病人,暗色絲孢黴病越來越常見。醫生在診斷這些病人時,應該考慮異常微生物的伺機皮膚感染。

Keywords: Cladophialophora, dematiaceous fungi, Exophiala jeanselmei, immunocompromised, Phaeohyphomycosis

關鍵詞: Cladophialophora、暗色孢屬真菌、甄氏外瓶黴、免疫功能低下、暗色絲孢黴病