Table of Content


Winter 2013, Vol. 21 No. 4

Hong Kong J. Dermatol. Venereol. (2013) 21, 191-195

Case Report

Using intralesional corticosteroids to treat significant periorbital oedema due to imatinib


YC Kho and S Lee 李啟焱


We report the first case of intralesional corticosteroids being successfully used to treat significant periorbital oedema secondary to imatinib therapy. The patient's quality of life was significantly impaired as a result of her ongoing imatinib treatment for an underlying malignancy. While this approach mitigates the risks associated with surgery, in rare cases it can result in retinochoroidal vascular occlusion from crystalline corticosteroid aggregates. Accordingly, periorbital corticosteroid injections should only be considered as a treatment option in carefully selected patients. Fortunately, our patient has thus far enjoyed a favourable outcome, with minimal periorbital oedema observed two years after dermatological intervention.


Keywords: Gastrointestinal stromal tumours, imatinib, periorbital oedema, intralesional steroid injections, quality of life improvement

關鍵詞: 胃腸道基質瘤、伊馬替尼、眼眶周圍水腫、病灶內注射類固醇、生活質素改善