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Winter 2013, Vol. 21 No. 4

Hong Kong J. Dermatol. Venereol. (2013) 21, 171-180


Original Article

Patch testing: clinical relevance and successful recall of allergens in local Chinese patients

斑貼試驗:本地華裔患者的臨床相關性和致敏原的成功憶述率

CFY Siu 蕭鳳兒 and TS Cheng 鄭天錫

Abstract

Objectives: To investigate the clinical relevance of contact allergens identified in patch testing, and the successful recall rate of these allergens. Methods: This was a single-centre study performed in Hong Kong. Local Chinese patients were invited for interviews. Results: There were a total of 146 patients with valid patch tests performed from 2009 to 2012. One hundred patients were interviewed, of which 68 patients had positive patch test reactions, resulting in a total of 122 allergen reactions. Nickel sulphate, fragrance mix, 5-chloro-2-methyl-4-isothiazolin-3-one+2-methyl-4-isothiazolin-3-one (3:1 in water) and paraphenylenediamine (PPD) were the commonest allergens identified in this study. Among these sixty-eight patients, 80.3% of the identified allergens were clinically relevant (45.9% definitely relevant, 34.4% probably or possibly relevant). 75.4% of the allergens were successfully recalled, either in their full names or substance groups. Patients with a lower education level were less likely to recall the allergens identified in patch testing. Conclusion: The clinical relevance of allergens and the recall rate were satisfactorily high.

目標:要找出在斑貼試驗確定的接觸性致敏原的臨床相關性及其成功憶述率。方法:這是在香港進行的單中心研究。本地華裔患者會被邀請會面。結果:由2009至2012年,總共有146名患者進行有效的斑貼試驗。一百名患者接受了採訪。六十八名有陽性斑貼試驗反應,共導致122次致敏原反應。在此研究中,硫酸鎳,混合香料,五-氯-二-甲基-四-異噻唑啉-三-酮+二-甲基-四-異噻唑啉-三-酮(在水中3:1)和對苯二胺是最常見的致敏原。在六十八名患者中,其致敏原標識的臨床相關性為80.3%(45.9%肯定有關,34.4%或許或可能有關)。患者能成功憶述75.4%的致敏原全名或物組群。教育程度較低的患者比較少能憶述在斑貼試驗確定的致敏原。結論:致敏原的臨床相關性和憶述率令人滿意。

Keywords: Patch test, allergic contact dermatitis, clinical relevance, recall

關鍵詞: 關鍵詞:斑貼試驗,過敏性接觸性皮炎,臨床相關性,憶述