Table of Content

Archive

Spring 2011, Vol. 19 No. 1

Hong Kong J. Dermatol. Venereol. (2011) 19, 6-13


Original Article

The prevalence of human papilloma virus in the anal region of male Chinese attendees in three public sexually transmitted disease clinics in Hong Kong

WY Leung 梁偉耀, PKS Chan 陳基湘, KH Lau 劉家豪, KM Ho 何景文

Abstract
Background and Objective: Human papilloma virus (HPV) infection is believed to be one of the primary causes of the rising trend of anal cancer. The aim of our study is to identify factors influencing the prevalence of HPV infection in anal region. Methods: This study was a cross-sectional one conducted from September 2008. Chinese male patients (with or without genital wart) attending three sexually transmitted disease clinics were consecutively invited to participate in the study on randomly chosen days between the study period. At the first visit, diseased patients and the control cases were asked to complete the questionnaire regarding the demographic data and sexual behaviors and swab specimens were collected blindly from the surface of peri-anal areas for HPV DNA detection. Results: A total of 160 men completed the study. On the basis of DNA analysis, the overall prevalence of anal HPV infection was found to be 16.9%. Of the men with anal HPV infection, 14.8% had an oncogenic HPV type. Risk factors independently associated with anal HPV were "presence of genital wart" and "Circumcision". Conclusion: The prevalence rate of anal HPV in this cross sectional study of STD attendees demonstrate that anal HPV infection is not uncommon in our locality. However, the prevalence rate oncogenic HPV type was relatively low compared with other studies. This study suggested that presence of genital wart and circumcision status might play important roles in HPV transmission in peri-anal area.