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Archive

Winter 2010, Vol. 18 No. 4

Hong Kong J. Dermatol. Venereol. (2010) 18, 204-208


Case Report

Failure to grow and infections in a baby with Netherton syndrome

TS Cheng 鄭天錫 and YC Giam 唐玉琴

Abstract
We report a Nepalese girl with Netherton syndrome, presenting as erythroderma. The child developed recurrent episodes of infection in her first year of life accompanied by poor physical development and failure to thrive. Gastroenterological studies did not show significant problems. The red skin continued to remain a challenge in management as it was raw and healed poorly except for the ankles and groins. The use of a ceramide-dominant barrier-repair emollient improved the skin condition. The skin barrier dysfunction highlights this child as a more difficult problem in skin dysfunction amongst the ichthyoses.