Table of Content


Spring 2010, Vol. 18 No. 1

Hong Kong J. Dermatol. Venereol. (2010) 18, 6-14

Original Article

Cutaneous angiosarcoma: a case series in Hong Kong

FC Ip 葉方正 and KC Lee 李景中

Background: Cutaneous angiosarcoma is a rare high grade malignant neoplasm in skin of endothelial differentiation. About 50% of cutaneous angiosarcoma affects head and neck region. Objective: To report a case series of primary cutaneous angiosarcoma in Hong Kong focusing in the clinical presentation and demographic features. Materials and method: Case records of patients from 2000 to 2009 with histopathological confirmation of the diagnosis of angiosarcoma were retrieved from the Social Hygiene Service clinics of the Department of Health of Hong Kong. Results: A total of 7 patients with primary cutaneous angiosarcoma were found. All patients were elderly with the age range from 72 to 91 years and a male predominance. Most patients could only be offered with palliative radiotherapy due to extensive disease upon presentation. The prognosis was generally poor. At the time of preparation of this manuscript, three patients has passed away and only one patient remains in remission. Conclusion: Cutaneous angiosarcoma is a high grade malignant neoplasm that mainly affected elderly men with poor prognosis. The tumor can mimic benign skin condition at the early stage and cause diagnostic delay. Clinicians should be alert of the diagnosis especially for suspicious lesions in the head and neck region in elderly patients so as to arrive at an early diagnosis.