Table of Content


Winter 2009, Vol. 17 No. 4

Hong Kong J. Dermatol. Venereol. (2009) 17, 204-208

Case Report

Recalcitrant scalp and intertriginous rash in a patient with diabetes insipidus: diversity of cutaneous manifestations and pitfalls in diagnosis of adult Langerhans histiocytosis

H Ranu and SH Pang

Langerhans cell histiocytosis (LCH) is a proliferative histiocytic disorder of unknown cause characterized by the accumulation of Langerhan cells in various tissues. Typically a disorder of childhood, features of this disease have been well documented in children but remain ambiguous and poorly documented in adults leading to many pitfalls in diagnosis. We report a case of Langerhans cell histiocytosis in a young lady who presented with cutaneous involvement of varying morphology and review the various cutaneous manifestations of adult Langerhans cell histiocytosis reported in the literature to date.