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Summer 2009, Vol. 17 No. 2

Hong Kong J. Dermatol. Venereol. (2009) 17, 69-77


Original Article

Depression in Hong Kong Chinese patients with psoriasis

F Chan 陳虎, KM Ho 何景文, AHT Pang 彭顯達

Abstract
Objective: The purpose of this study is to examine the point prevalence of depressive disorders, health-related quality of life (HRQoL) and their clinical correlates in a group of Hong Kong Chinese patients with psoriasis. Method: This was a cross-sectional study held in two public dermatology clinics between 1st July 2007 and 30th January 2008. A total of 221 Chinese patients with psoriasis were recruited. All participants were interviewed by the principal investigator using the Chinese-Bilingual Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition Axis I, Patient Version (CB-SCID-I/P) to identify patients with a diagnosis of depressive disorders and other psychiatric disorders according to the Diagnostic and Statistical Manual of Mental Disorder, Fourth Edition. The severity of depression was assessed by using Hamilton Depression Rating Scale (HAM-D), and self-rated Beck Depression Inventory (BDI). The severity of psoriasis was assessed by the dermatologists using Psoriasis Area and Severity Index (PASI). The Psoriasis Disability Index (PDI) was adopted to measure the HRQoL of the subjects. Results: The point prevalence of 'any kind of depressive disorder' (AD) was 26.4%. History of depression and PASI score were found to be the independent predictors of depression in patients with psoriasis. Regarding the HRQoL, a statistically significant difference in the mean score of PDI was found between the AD (37.09, standard deviation=18.06) and 'no psychiatric diagnosis' (NP) (13.72, standard deviation=15.42) groups (p<0.001). It was found that severity of depression accounted for 71.4% of the total variance of HRQoL in linear regression. Only 15.5% of depressed psoriatic patients were referred for psychiatric treatment. Conclusion: This study showed that our sample of Chinese patients with psoriasis had similar point prevalence of depression comparable to their Western counterparts. Depression in psoriatic patients was often unrecognized and untreated.