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Spring 2009, Vol. 17 No. 1

Hong Kong J. Dermatol. Venereol. (2009) 17, 30-34


Case Report

Primary biliary cirrhosis in a patient with generalised morphoea

Y Kim, S Lee 李啟焱, J Choi

Abstract
A 66-year-old Chinese man with primary biliary cirrhosis (PBC) presented with a twelve-month history of skin thickening and tightness across his chest. After a skin biopsy and immunological investigations, a diagnosis of generalised morphoea (GM) was made. His GM markedly improved with nine months of colchicine therapy. To our knowledge there have been only two previously reported cases of PBC associated with GM. Difficulties with treatment of GM are discussed.