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Summer 2007, Vol. 15 No. 2

Hong Kong J. Dermatol. Venereol. (2007) 15, 62-67


Original Article

Psoriatic arthritis in Hong Kong

YY Leung 梁盈盈, EK Li 李國銘, MH Leung 梁滿豪, EWL Kun 靳惠蓮, LS Chiu 趙麗珊

Abstract
Objectives: To study the clinical features and disease burden in patients with psoriatic arthritis (PsA) in Chinese. Methods: A cross-sectional study on clinical features, laboratory data and radiography in patients with PsA in rheumatology clinics. Results: One hundred and twenty-seven patients studied with mean (+/-SD) duration of PsA 11.58 (+/-7.47) years. Symmetrical polyarthritis developing in the third decade with an equal male to female ratio was the commonest pattern of arthritis. Seventy percent of patients required disease modifying antirheumatic drugs (DMARDs) and 21.3% had used two or more DMARDs. at some time for control of joint disease. Clinical classification identified predominant axial disease (AD) and predominant peripheral disease (PD) in 11% and 89% respectively; while radiographical classification identified AD and peripheral disease PD in 36.2% and 63.8%. Radiographic sacroiliitis were asymptomatic in 43%. A third of patients (33%) stopped working because of the disease. Patients with PsA had severe impairment of quality of life as compared to the normal population in Hong Kong. Differentiation into axial or peripheral disease by either classification systems did not affect quality of life outcomes and disease burden. Conclusion: The commonest pattern of PsA in Chinese was symmetrical polyarthritis. Patients with PsA were associated with a high disease burden and poor quality of life. More studies should be done to find out the predictors for poor prognosis in order to improve the quality of life for these patients.