Table of Content


Autumn 2004, Vol. 12 No. 3

H.K. Dermatol. Venereol. Bull. (2004) 12, 126-132

Original Article

Pemphigus foliaceus: a clinical study of 32 cases in Hong Kong

HC Cheung 張謙昌

This is a cross-sectional, retrospective study of 32 Hong Kong Chinese patients with pemphigus foliaceus from the year 1993 to 2003. The incidence was 0.48 per million population per year. There were 24 males and 8 females and the mean onset age was 55. Seventeen patients presented with generalised disease and one with erythroderma. There was a correlation of anti-skin titre versus disease severity. Twenty-seven patients required systemic prednisolone with a mean dose of 36 mg daily for the first disease remission. Dapsone was not an effective treatment. When azathioprine was used as an adjuvant, the mortality and remission rates were 0% and 40% respectively. Disease or treatment related deaths occurred within the first three months. The average onset age for the deceased was 73.7 in compare with 52.4 for the survivors.