Table of Content

Current Issue

Spring/Summer 2025, Vol. 32 No. 1

Hong Kong J. Dermatol. Venereol. (2025) 32, 66-70


Case Report

Extensive calciphylaxis supported by alarming simple imaging in a renal patient

令人震驚的簡單放射成像確立一名腎病患者的廣泛性鈣化防禦症

SSH Ng 伍善恆 and SC Ng 吳順展

Abstract

Calciphylaxis, also known as calcific uraemic arteriolopathy, is a rare cutaneous manifestation of systemic disease occurring in patients with chronic kidney disease. It typically presents as a painful necrotic and progressive skin ulcer of reticular pattern, mostly in the lower legs. It is a condition of substantial morbidity and mortality, with death most frequently due to sepsis. Although skin biopsy is a standard method to confirm the clinical diagnosis, non-invasive imaging often provides valuable clues. We report a case of extensive calciphylaxis in a lady with end-stage renal failure, where clinical radiography showed a typical net-like calcifications.

鈣化防禦症，也被稱為「鈣性尿毒症性小動脈病」，是一種發生於慢性腎臟病患者系統疾病的罕見皮膚表現。它通常表現為疼痛性的皮膚壞死和網狀的漸進性皮膚潰瘍，主要發生在小腿。這是一種發病率和死亡率都很高的疾病，最常見的死因是敗血症。儘管皮膚活檢是確認臨床上懷疑鈣化防禦症的標準方法，但非侵入性的影像亦可以提供有價值的診斷線索。我們報告了一位患有末期腎衰竭的女士的廣泛鈣化防禦症的病例，放射線成像顯示典型的網狀鈣化。

Keywords: Calcific uraemic arteriolopathy, Calciphylaxis, Net-like calcifications

關鍵詞: 鈣性尿毒症性小動脈病、鈣化防禦症、網狀鈣化