Table of Content

Current Issue

Summer 2020, Vol. 28 No. 2

Hong Kong J. Dermatol. Venereol. (2020) 28, 55-62


Original Article

Evaluation of metabolic syndrome and its components in patients with rosacea: a cross-sectional, case-control study

玫瑰痤瘡患者中的代謝綜合徵及其成分的評估:一項橫斷面病例對照研究

O Ozbagcivan, T Ozturk, S Akarsu, T Ilknur, E Fetil

Abstract

Introduction: Previous studies have suggested an association between cardiovascular disease and rosacea. However, there is still a paucity of data regarding its association with metabolic syndrome (MetS). Methods: The components of MetS were evaluated in 100 rosacea patients and 100 controls. Results: MetS was determined in 44% of the rosacea patients and 35% of the controls. Although the difference was not statistically significant (p=0.193), rosacea patients were more likely to have dyslipidaemia (p<0.001), insulin resistance (p=0.035), hypertension (p=0.009), higher atherogenic index (p<0.001) and a higher hypercoagulability (p=0.025) and inflammatory state (p=0.003) compared to controls. Conclusion: The results of this study support that rosacea patients should be screened routinely for the components of MetS such as dyslipidaemia, insulin resistance, hypertension and other cardiovascular risk factors.

簡介:先前的研究證明心血管疾病和玫瑰痤瘡之間存在關聯。然而,關於其與代謝綜合徵的關聯,仍缺乏數據。方法:在各100名玫瑰痤瘡患者和對照組人仕中,評估了他們有否代謝綜合徵成分。結果:44%的玫瑰痤瘡患者和35%的對照組人仕被測定為有代謝綜合徵。儘管無統計學意義上的差異(p=0.193),但與對照組相比,玫瑰痤瘡患者較大機會患上血脂異常(p<0.001)、胰島素阻抗(p=0.035)、高血壓(p=0.009)、較高的致動脈粥樣硬化指數(p<0.001)、較高的血液高凝狀態 (p=0.025) 和發炎狀態 (p=0.003)。結論:這項研究結果支持玫瑰痤瘡患者應定期篩查有否代謝綜合徵成分,例如血脂異常、胰島素阻抗、高血壓和其他心血管危險因子。

Keywords: Cardiovascular risk factors, metabolic syndrome, rosacea

關鍵詞: 心血管危險因子、代謝綜合徵、玫瑰痤瘡