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Spring 2020, Vol. 28 No. 1

Hong Kong J. Dermatol. Venereol. (2020) 28, 25-29


Case Report

Eruptive mid-dermal elastolysis: report of a case and brief review of the literature

發疹性真皮中部彈性組織溶解:一例報告及簡要文獻回顧

EÖ Durmaz, D Duman, E Sezer, ED Çetin, S Şahin

Abstract

Mid-dermal elastolysis (MDE) is a rare, acquired, idiopathic disorder of elastic tissue, characterised clinically by macules and plaques with superficial fine wrinkling and histologically by focal loss of elastic tissue in the reticular dermis. Herein we present a 26-year-old female patient with eruptive MDE and briefly review the current literature. Except for stressful life events recently, no causative factor could be elicited from personal history. A trial of topical medications was ineffective both in reducing the unsightly appearance and in halting MDE progression. Awareness of the condition and reporting of successful therapeutic experiences might enable appropriate management of affected patients.

真皮中部彈性組織溶解是一種罕見的後天特發性的彈性組織疾病,其特徵是臨床上表現為表面有細微皺紋斑點和斑塊,組織學上表現則為網狀真皮中彈性組織的局部損失。本文闡述了一名26歲的女性患者的發疹性真皮中部彈性組織溶解病例,並簡要回顧當前文獻。除了最近的生活壓力外,問診中未能找到因果關係因素。外用藥物的試驗,均未能改善患者因此病導致的外觀影響或阻止病情繼續。對此病的認識及成功治療經驗的報告可以有效提高受影響患者得到適切治療的機會。

Keywords: Anetoderma, elastic tissue disorders, elastolytic disorders, mid-dermal elastolysis

關鍵詞: 皮膚鬆弛症、彈性組織疾病、彈性溶解疾病、真皮中部彈性組織溶解