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Spring 2020, Vol. 28 No. 1

Hong Kong J. Dermatol. Venereol. (2020) 28, 19-23


Case Report

Squamoid eccrine ductal carcinoma: an extremely rare variant of sweat duct carcinoma

鱗狀小汗腺導管癌:汗管癌的一種極罕見變異

H Şahin, FE Kombak, ZD Akdeniz Doğan, L Cinel

Abstract

Squamoid eccrine ductal carcinoma (SEDC) is an extremely rare variant of sweat duct carcinoma. Herein, we report a case of an 80-year-old female who presented with an ulcerated plaque on her forehead. An initial punch biopsy revealed an invasive tumour with squamous features. Subsequently, excisional biopsy revealed squamous and ductal areas, with frequent mitosis and extensive perineural invasion. The patient has been disease-free for four years. SEDCs have a better prognosis than other sweat duct carcinomas. Differential diagnoses for SEDCs include squamous cell carcinoma, microcystic adnexal carcinoma, porocarcinoma and metastatic tumours. There is a high possibility of misdiagnosing SEDC as squamous cell carcinoma, particularly in small punch and shave biopsies.

鱗狀小汗腺導管癌是汗管癌的一種極罕見變異。在此,我們報告了一例80歲女性的額頭上有潰瘍斑塊,最初的鑽取活檢顯示為具有鱗狀特徵的侵襲性腫瘤;隨後的切除活檢則顯示分別有鱗狀和導管區域,可見頻繁的有絲分裂和廣泛的神經旁侵犯。該患者診斷後已無病四年,正印證了鱗狀小汗腺導管癌的預後比其他汗管癌好。鱗狀小汗腺導管癌的鑑別診斷包括鱗狀細胞癌、微囊腫性附件癌、汗孔癌和轉移性腫瘤。鱗狀小汗腺導管癌誤診為鱗狀細胞癌的可能性很高,尤其是在細小樣本的鑽取和刮取活檢。

Keywords: Microcystic adnexal carcinoma, squamoid eccrine ductal carcinoma, sweat duct carcinoma

關鍵詞: 微囊腫性附件癌、鱗狀小汗腺導管癌、汗管癌